Sobre el grupo
Investigador Principal
Ana Cenarro Lagunas
Equipo
Ana María Bea Sanz, Daniel Bello Álvarez, Fernando Civeira Murillo, Irene Gracia Rubio, Estíbaliz Jarauta Simón, Martín Laclaustra Gimeno, Itziar Lamiquiz Moneo, Ángela Lezcano Enciso, Victoria Marco Benedí, Rocío Mateo Gallego, Rebeca Monjón González, Mª Rosario Pérez Ruiz, Carmen Rodrigo Carbó
Hospital Universitario Miguel Servet
Universidad de Zaragoza
Líneas de Investigación
Bases genéticas de las hipercolesterolemias primarias
Relación fenotipo-genotipo en la hipercolesterolemia familiar
Scores genéticos en las dislipemias primarias
Predicción riesgo cardiovascular
Publicaciones más relevantes
Sánchez-Hernández RM, Civeira F. Homozygous familiar hypercholesterolemia: still a long way to go. Lancet. 2022 Feb 19;399(10326):696-697. doi: 10.1016/S0140-6736(21)02223-6. Epub 2022 Jan 28. PMID: 35101174. FI-98,4
de la Rosa L, Garcia-Ruiz C, Vallejo C, Baulies A, Nunez S, Monte M, Marin J, Baila Rueda L, Cenarro Lagunas A, Civeira Murillo F, Fuster J, Garcia-Valdecasas J, Ferrer J, Karin M, Ribas V, Fernandez-Checa J. STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway. JOURNAL OF HEPATOLOGY. 2021. 10.1016/j.jhep.2021.01.028. FI-26,8
Guijarro C, Civeira Murillo F, Masana L. Genetic Confirmation of Monogenic Familial Hypercholesterolemia Advises a More Intensive Lipid-Lowering Approach.. JAMA Cardiology. 2020. 10.1001/jamacardio.2020.4114. FI-14,7
Larrea-Sebal A, Sasiain I, Jebari-Benslaiman S, Galicia-Garcia U, Uribe K, Benito-Vicente A, Gracia Rubio I, Bediaga-Bañeres H, Arrasate S, Cenarro Lagunas A, Civeira Murillo F, González-Díaz H, Martin Plagaro C. OptiMo-LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic Residues.. Advanced Science. 2024. 10.1002/advs.202305177. FI-14,3
Donat-Vargas C, Moreno Franco M, Laclaustra Gimeno M, Sandoval-Insausti H, Jarauta Simón E, Guallar-Castillon P. Exposure to dietary polychlorinated biphenyls and dioxins, and its relationship with subclinical coronary atherosclerosis: The Aragon Workers' Health Study. ENVIRONMENT INTERNATIONAL. 2020. 10.1016/j.envint.2019.105433. FI-10,3
Pérez Calahorra S, Civeira Murillo F, Guallar-Castillon P, Pinto X, Banegas J, Pedro-Botet J, Suarez-Tembra M, Mauri M, Soler C, Rodriguez-Artalejo F, Laclaustra Gimeno M. Behavioural cardiovascular risk factors and prevalence of diabetes in subjects with familial hypercholesterolaemia. European Journal of Preventive Cardiology. 2020. 10.1177/2047487319896138. FI-8,6
Larrea-Sebal A, Benito-Vicente A, Fernandez-Higuero J, Jebari-Benslaiman S, Galicia-Garcia U, Uribe K, Cenarro Lagunas A, Ostolaza H, Civeira Murillo F, Arrasate S, Gonzalez-Diaz H, Martin C. MLb-LDLr A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants. JACC-BASIC TO TRANSLATIONAL SCIENCE. 2021. 10.1016/j.jacbts.2021.08.009. FI-8,4
Domingo-Relloso A, Bozack A, Kiihl S, Rodriguez-Hernandez Z, Rentero-Garrido P, Casasnovas Lenguas J, León Latre M, Garcia-Barrera T, Luis Gomez-Ariza J, Moreno Franco M, Cenarro Lagunas A, de Marco G, Parvez F, Siddique A, Shahriar H, Uddin M, Islam T, Navas-Acien A, Gamble M, Tellez-Plaza M. Arsenic exposure and human blood DNA methylation and hydroxymethylation profiles in two diverse populations from Bangladesh and Spain. ENVIRONMENTAL RESEARCH. 2022. 10.1016/j.envres.2021.112021. FI-7,7
Mérida D, Acosta-Reyes J, Bayán-Bravo A, Moreno Franco M, Laclaustra Gimeno M, Guallar-Castillón P. Phthalate exposure and subclinical carotid atherosclerosis: A systematic review and meta-analysis.. ENVIRONMENTAL POLLUTION. 2024. 10.1016/j.envpol.2024.124044. FI-7,6
Mérida D, Moreno Franco M, Marquès M, León Latre M, Laclaustra Gimeno M, Guallar-Castillón P. Phthalate exposure and the metabolic syndrome: A systematic review and meta-analysis.. ENVIRONMENTAL POLLUTION. 2023. 10.1016/j.envpol.2023.121957. FI-7,6