Sobre el grupo


Investigador Principal

Fernando Civeira Murillo 

Equipo

Ana Cenarro Lagunas, Ana María Bea Sanz, Ángela Lezcano Enciso, Carmen Rodrigo Carbó, Estíbaliz Jarauta Simón, Irene Gracia Rubi, Itziar Lamiquiz Moneo, Lucia Baila Rueda, Mª Rosario Pérez Ruiz, Marcos Clavero Adell, María Civeira Marín, María Ramos Cáceres, Martín Laclaustra Gimeno, Rebeca Monjón González, Rocío Mateo Gallego, Victoria Marco Benedí

Hospital Universitario Miguel Servet

Universidad de Zaragoza

Líneas de Investigación


Marcadores inflamatorios y arteriosclerosis en las Hipercolesterolemias Autosómicas dominantes

Nuevos loci responsables de Hipercolesterolemias autosómicas dominantes (HAD)

Regeneración miocárdica

Relación entre fenotipo y genotipo en las hipercolesterolemias autosómicas dominantes (HAD)

Publicaciones más relevantes


Ariza M, Rioja J, Ibarretxe D, Camacho A, Diaz-Diaz J, Mangas A, Carbayo-Herencia J, Ruiz-Ocana P, Lamiquiz-Moneo I, Mosquera D, Saenz P, Masana L, Muniz-Grijalvo O, Perez-Calahorra S, Valdivielso P, Spanish Dyslipidemia Registry. Molecular basis of the familial chylomicronemia syndrome in patients from the National Dyslipidemia Registry of the Spanish Atherosclerosis Society. J. Clin. Lipidol.. 2018. 12(6): 1482 - 1492. 10.1016/j.jacl.2018.07.013.

Calmarza P, Lapresta C, Martinez M, Lahoz R, Povar J. Utility of myeloperoxidase in the differential diagnosis of acute coronary syndrome. Arch Cardiol Mex. 2018. 88(5): 391 - 396. 10.1016/j.acmx.2017.11.003.

Manios Y, Androutsos O, Lambrinou C, Cardon G, Lindstrom J, Annemans L, Mateo-Gallego R, de Sabata M, Iotova V, Kivela J, Martinez R, Moreno L, Rurik I, Schwarz P, Tankova T, Liatis S, Makrilakis K, Feel4Diabet Study Grp. A school- and community-based intervention to promote healthy lifestyle and prevent type 2 diabetes in vulnerable families across Europe: design and implementation of the Feel4Diabetes-study. Public Health Nutr.. 2018. 21(17): 3281 - 3290. 10.1017/S1368980018002136.

Castro-Castro M, Candas-Estebanez B, Esteban-Salan M, Calmarza P, Arrobas-Velilla T, Romero-Roman C, Pocovi-Mieras M, Aguilar-Doreste J, Commission Lipoprot Vasc Dis, Soc Espanola Quim Clinica. Removing Lipemia in Serum/Plasma Samples: A Multicenter Study. Ann Lab Med. 2018. 38(6): 518 - 523. 10.3343/alm.2018.38.6.518.

Benito-Vicente A, Uribe K, Siddiqi H, Jebari S, Galicia-Garcia U, Larrea-Sebal A, Cenarro A, Stef M, Ostolaza H, Civeira F, Palacios L, Martin C. Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition. PLoS One. 2018. 13(10): e0204771. 10.1371/journal.pone.0204771.

Ruiz-Iruela C, Padro-Miquel A, Pinto-Sala X, Baena-Diez N, Caixas-Pedragos A, Guell-Miro R, Navarro-Badal R, Jusmet-Miguel X, Calmarza P, Puzo-Foncilla J, Alia-Ramos P, Candas-Estebanez B. KIF6 gene as a pharmacogenetic marker for lipid-lowering effect in statin treatment. PLoS One. 2018. 13(10): e0205430. 10.1371/journal.pone.0205430.

Lutjohann D, Bjorkhem I, Friedrichs S, Kerksiek A, Geilenkeuser W, Lovgren-Sandblom A, Ansorena D, Astiasaran I, Baila-Rueda L, Barriuso B, Bretillon L, Browne R, Caccia C, Cenarro A, Crick P, Fauler G, Garcia-Llatas G, Griffiths W, Iuliano L, Lagarda M, Leoni V, Lottenberg A, Matysik S, McDonald J, Rideout T, Schmitz G, Nunes V, Wang Y, Zerbinati C, Diczfalusy U, Schott H. International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods. Biochimie. 2018. 153: 26 - 32. 10.1016/j.biochi.2018.07.016.

Mateo-Gallego R, Lacalle L, Perez-Calahorra S, Marco-Benedi V, Recasens V, Padron N, Lamiquiz-Moneo I, Baila-Rueda L, Jarauta E, Calmarza P, Cenarro A, Civeira F. Efficacy of repeated phlebotomies in hypertriglyceridemia and iron overload: A prospective, randomized, controlled trial. J. Clin. Lipidol.. 2018. 12(5): 1190 - 1198. 10.1016/j.jacl.2018.06.017.

Laclaustra M, Lopez-Garcia E, Civeira F, Garcia-Esquinas E, Graciani A, Guallar-Castillon P, Banegas J, Rodriguez-Artalejo F. LDL Cholesterol Rises With BMI Only in Lean Individuals: Cross-sectional US and Spanish Representative Data. Diabetes Care. 2018. 41(10): 2195 - 2201. 10.2337/dc18-0372.

Marco-Benedi V, Lamiquiz-Moneo I, Alvarez-Sala L, Civeira F. Disappearance of recurrent pancreatitis after splenectomy in familial chylomicronemia syndrome. Atherosclerosis. 2018. 275: 342 - 345. 10.1016/j.atherosclerosis.2018.06.870.

Hegele R, Berberich A, Ban M, Wang J, Digenio A, Alexander V, D'Erasmo L, Arca M, Jones A, Bruckert E, Stroes E, Bergeron J, Civeira F, Witztum J, Gaudet D. Clinical and biochemical features of different molecular etiologies of familial chylomicronemia. J. Clin. Lipidol.. 2018. 12(4): 920 - 927. 10.1016/j.jacl.2018.03.093.

Garcia-Esquinas E, Ortola R, Galan I, Soler-Vila H, Laclaustra M, Rodriguez-Artalejo F. Moderate alcohol drinking is not associated with risk of depression in older adults. Sci Rep. 2018. 8(1): 11512 - 11512. 10.1038/s41598-018-29985-4.

Moreno-Franco B, Perez-Tasigchana R, Lopez-Garcia E, Laclaustra M, Gutierrez-Fisac J, Rodriguez-Artalejo F, Guallar-Castillon P. Socioeconomic determinants of sarcopenic obesity and frail obesity in community-dwelling older adults: The Seniors-ENRICA Study. Sci Rep. 2018. 8: 10760. 10.1038/s41598-018-28982-x.

Redondo I, Romero R, Calmarza P, Munoz A, Martinez G, Aizpun J. Vitamin D deficiency in a healthy Aragonese pediatric population. Nutr. Hosp.. 2018. 35(4): 782 - 788. 10.20960/nh.1592.

Calmarza P, Paris A, Lopez C, Barrio M, Carceller D. Vitamin D levels in patients with recent cancer diagnosis. Nutr. Hosp.. 2018. 35(4): 903 - 908. 10.20960/nh.1675.

Civeira F, Pocovi M. Familial hypercholesterolemia in pediatric patients. The success begins here. Clin. Invest. Arterioscler.. 2018. 30(4): 179 - 180. 10.1016/j.arteri.2018.06.001.

Blasco-Colmenares E, Moreno-Franco B, Latre M, Mur-Vispe E, Pocovi M, Jarauta E, Civeira F, Laclaustra M, Casasnovas J, Guallar E. Sleep duration and subclinical atherosclerosis: The Aragon Workers' Health Study. Atherosclerosis. 2018. 274: 35 - 40. 10.1016/j.atherosclerosis.2018.05.003.

Uzhova I, Mateo-Gallego R, Moreno-Franco B, Molina-Montes E, Leon-Latre M, Lenguas J, Civeira F, Penalvo J. The additive effect of adherence to multiple healthy lifestyles on subclinical atherosclerosis: Insights from the AWHS. J. Clin. Lipidol.. 2018. 12(3): 615 - 625. 10.1016/j.jacl.2018.03.081.

Laclaustra M, Rodriguez-Artalejo F, Guallar-Castillon P, Banegas J, Graciani A, Garcia-Esquinas E, Ordovas J, Lopez-Garcia E. Prospective association between added sugars and frailty in older adults. Am J Clin Nutr. 2018. 107(5): 772 - 779. 10.1093/ajcn/nqy028.

Gijon-Conde T, Graciani A, Lopez-Garcia E, Garcia-Esquinas E, Laclaustra M, Ruilope L, Rodriguez-Artalejo F, Banegas J. Frailty, Disability, and Ambulatory Blood Pressure in Older Adults. J. Am. Med. Dir. Assoc.. 2018. 19(5): 433 - 438. 10.1016/j.jamda.2017.11.014.

Lamiquiz-Moneo I, Pérez-Ruiz MR, Jarauta E, Tejedor MT, Bea AM, Mateo-Gallego R, Pérez-Calahorra S, Baila-Rueda L, Marco-Benedí V, de Castro-Orós I, Cenarro A, Civeira F. Single Nucleotide Variants Associated With Polygenic Hypercholesterolemia in Families Diagnosed Clinically With Familial Hypercholesterolemia.. Rev Esp Cardiol (Engl Ed). 2018. 71(5): 351 - 356. 10.1016/j.rec.2017.07.010.

Baila-Rueda L, Cenarro A, Lamiquiz-Moneo I, Perez-Calahorra S, Bea A, Marco-Benedi V, Jarauta E, Mateo-Gallego R, Civeira F. Cholesterol oversynthesis markers define familial combined hyperlipidemia versus other genetic hypercholesterolemias independently of body weight. J. Nutr. Biochem.. 2018. 53: 48 - 57. 10.1016/j.jnutbio.2017.10.005.

Lozano-Gerona J, Garcia-Otin A. ImageJ-based semiautomatic method to analyze senescence in cell culture. Anal. Biochem.. 2018. 543: 30 - 32. 10.1016/j.ab.2017.11.020.

Mateo-Gallego R, Lamiquiz-Moneo I, Perez-Calahorra S, Marco-Benedi V, Bea A, Baila-Rueda L, Laclaustra M, Penalvo J, Civeira F, Cenarro A. Different protein composition of low-calorie diet differently impacts adipokine profile irrespective of weight loss in overweight and obese women. Nutr. Metab. Carbiovasc. Dis.. 2018. 28(2): 133 - 142. 10.1016/j.numecd.2017.10.024.

Sanchez-Hernandez R, Prieto-Matos P, Civeira F, Lafuente E, Vargas M, Real J, Goicoechea F, Fuentes F, Pocovi M, Boronat M, Wagner A, Masana L. Autosomal recessive hypercholesterolemia in Spain. Atherosclerosis. 2018. 269: 1 - 5. 10.1016/j.atherosclerosis.2017.12.006.

Baila-Rueda L, Lamiquiz-Moneo I, Jarauta E, Mateo-Gallego R, Perez-Calahorra S, Marco-Benedi V, Bea A, Cenarro A, Civeira F. Association between non-cholesterol sterol concentrations and Achilles tendon thickness in patients with genetic familial hypercholesterolemia. J. Transl. Med.. 2018. 16(1): 6 - 6. 10.1186/s12967-018-1380-3.

Olivan-Viguera A, Garcia-Otin A, Lozano-Gerona J, Abarca-Lachen E, Garcia-Malinis A, Hamilton K, Gilaberte Y, Pueyo E, Kohler R. Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes. PLoS One. 2018. 13(1): e0190307. 10.1371/journal.pone.0190307.

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