GIIS054-Proteintargets

Redrado-Hernández S, Macías-León J, Castro-López J, Belén Sanz A, Dolader Ballesteros E, Arias Cabrero M, González-Ramírez A, Sánchez-Navarro D, Petryk Y, Farkaš V, Vincke C, Muyldermans S, García-Barbazán I, del Agua Arias-Camisón C, Zaragoza O, Arroyo J, Pardo Jimeno J, Gálvez Buerba E, Hurtado Guerrero R. Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal ß-1,3-Glucanosyltransferases. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 10.1002/anie.202405823. Q-1. F.I-17

Bellin L, Del Cano-Ochoa F, Velázquez Campoy A, Moehlmann T, Ramon-Maiques S. Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase Nature Communications. 10.1038/s41467-021-21165-9. Q-1. F.I-15,7

Albert M, Uranga Murillo I, Arias Cabrero M, de Miguel Samaniego D, Peña Fresneda N, Montinaro A, Varanda A, Theobald S, Areso I, Saggau J, Koch M, Liccardi G, Peltzer N, Rybniker J, Hurtado Guerrero R, Merino P, Monzón Garcés M, Badiola Díez J, Reindl-Schwaighofer R, Sanz Pamplona R, Cebollada Solanas A, Megyesfalvi Z, Dome B, Secrier M, Hartmann B, Bergmann M, Pardo Jimeno J, Walczak H. Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality. CELL DEATH AND DIFFERENTIATION. 10.1038/s41418-024-01278-6. Q-1. F.I-15,4

Banos-Jaime B, Uceda-Mayo A, Rivero-Rodriguez F, Casado-Combreras M, Velazquez-Cruz A, Velázquez Campoy A, Corrales-Guerrero L, de la Rosa M, Diaz-Moreno I. Evolutionary Pro-To-Thr Mutation in the Intrinsically Disordered Domain of ANP32 Family Members Modulates Their Target Binding Modes Advanced Science. 10.1002/advs.202415566. Q-1. F.I-14,1

Baños-Jaime B, Corrales-Guerrero L, Pérez-Mejías G, Rejano-Gordillo C, Velázquez Campoy A, Martínez-Cruz L, Martínez-Chantar M, De la Rosa M, Díaz-Moreno I. Phosphorylation at the disordered N-end makes HuR accumulate and dimerize in the cytoplasm. NUCLEIC ACIDS RESEARCH. 10.1093/nar/gkae564. Q-1. F.I-13,1

Ortega Alarcón D, Claveria Gimeno R, Vega Sánchez S, Kalani L, Jorge-Torres O, Esteller M, Ausio J, Abián Franco O, Velázquez Campoy A. Extending MeCP2 interactome: canonical nucleosomal histones interact with MeCP2. NUCLEIC ACIDS RESEARCH. 10.1093/nar/gkae051. Q-1. F.I-13,1

Lozano-Juste J, Infantes L, Garcia-Maquilon I, Ruiz-Partida R, Merilo E, Benavente J, Velázquez Campoy A, Coego A, Bono M, Forment J, Pampín B, Destito P, Monteiro A, Rodríguez R, Cruces J, Rodriguez P, Albert A. Structure-guided engineering of a receptor-agonist pair for inducible activation of the ABA adaptive response to drought. Science Advances. 10.1126/sciadv.ade9948. Q-1. F.I-12,5

Rivero-Rodriguez F, Diaz-Quintana A, Velazquez-Cruz A, Gonzalez-Arzola K, Gavilan M, Velázquez Campoy A, Rios R, De la Rosa M, Diaz-Moreno I. Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c Redox Biology. 10.1016/j.redox.2021.101967. Q-1. F.I-11,9

Di X, Ortega-Alarcon D, Kakumanu R, Iglesias-Fernandez J, Diaz L, Baidoo E, Velázquez Campoy A, Rodríguez-Concepción M, Perez-Gil J. MEP pathway products allosterically promote monomerization of  deoxy-D-xylulose-5-phosphate synthase to feedback regulate their supply. Plant Communications. 10.1016/j.xplc.2022.100512. Q-1. F.I-11,6

González-Arzola K, Díaz-Quintana A, Bernardo-García N, Martínez-Fábregas J, Rivero-Rodríguez F, Casado-Combreras M, Elena-Real C, Velázquez-Cruz A, Gil-Caballero S, Velázquez Campoy A, Szulc E, Gavilán M, Ayala I, Arranz R, Ríos R, Salvatella X, Valpuesta J, Hermoso J, De la Rosa M, Díaz-Moreno I. Nucleus-translocated mitochondrial cytochrome c liberates  nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar  liquid-liquid phase separation. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 10.1038/s41594-022-00842-3. Q-1. F.I-10,1