FutureFoodS – Second Joint Transnational Co-funded Call
27 enero, 2026EP PerMed JTC 2026
27 enero, 2026The call, «Resolving unsolved cases in rare genetic and non-genetic diseases» welcomes proposals focused on providing diagnostic clarity in unsolved rare genetic and non-genetic diseases.
Involving patient organisations from the very start is highly desirable. Should you need guidance about patient involvement in research, check out this guide.
The goal is to solve Undiagnosed Rare Genetic diseases and to address complex, multifactorial Rare Non-Genetic diseases by identifying causative variants in patients with no molecular diagnosis after prior genetic or genomic testing and providing diagnostic clarity for conditions of unknown or mixed pathogenesis.
Focus areas:
- Functional validation to classify variants of uncertain significance and increase the diversity of functional genomics research, or validation of candidate VUS to improve outcomes for a broader range of patients using in silico, in vitro or animal model systems
- Use of multi-omics or integrative methods to resolve ambiguous or complex variants
- New tools/methodologies not yet validated in clinical setting, including biostatistics, advanced bioinformatics, and mathematics approaches
- Systems biology and disease mechanism modelling
- Integration of clinical, environmental, lifestyle, and sensor-derived data
- Development of knowledge graphs or disease maps to link ohenotypic and mechanistic insights
- Use of advanced AI and modelling tools
Deadline: 12 February 2026