IpIBA seminar series 2022/2023 “Antitumor effects of antipsychotic phenothiazines in glioblastoma cells”
Glioblastoma is the most aggressive primary brain tumor in adults. Efficiency of current diagnostic methods and therapeutic strategies of glioblastoma is narrowed by the presence of the molecular-restrictive blood-brain barrier (BBB), and the belated translation of relevant biomarkers into the clinical practice. New efforts emerge towards a personalized medicine, based on molecularly matched formulations against specific tumor biomarkers of this heterogeneous tumor. Due to their molecular features, nanobodies emerge as novel promising immunotargeted tools for glioblastoma.
In the present in vitro study we tested the efficacy and the cellular effects of two antipsychotic phenothiazines (Chlorpromazine and thioridazine) in GBM cells
Speaker: Lucía Ferro Sánchez
Sala de Grados, Faculty of Medicine, main metting room and online via zoom.
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